Table 1.

Distribution of selected characteristics of prostate cancer cases and population-based controls

	Cases (N=1308)		Controls (N=1266)		p-value*
	N	%	N	%
Age at Reference Date
35–49	102	7.8	107	8.4
50–54	188	14.4	178	14.1
55–59	325	24.8	343	27.1
60–64	395	30.2	334	26.4
65–69	153	11.7	160	12.6
70–74	145	11.1	144	11.4
BMI
<25.0	429	32.8	389	30.7
25.0–29.9	637	48.7	618	48.8
≥30	242	18.5	259	20.5	0.34
Smoking History
Never	522	39.9	541	42.7
Former	631	48.2	561	44.3
Current	155	11.9	164	13.0	0.13
Family History of PC‡
No	1025	78.4	1124	88.8
Yes	283	21.6	142	11.2	<0.0001
PSA Screening History
Never	135	10.3	167	13.2
DRE only	223	17.1	483	38.1
PSA	950	72.6	616	48.7	<0.0001
PSA Level ± (ng/mL)
0–3.9	178	13.6	1175	92.8
4–9.9	722	55.2	74	5.8
10–19.9	190	14.5	15	1.2
≥20	118	9.0	2	0.2
Missing	100	7.7	0	0.0	<0.0001
Gleason Score
2–4	67	5.1
5–6	680	52.0
7=3+4	355	27.1
7=4+3	76	5.8
8–10	126	9.6
Missing	4	0.3
Stage of Disease
Local	1022	78.1
Regional	254	19.4
Distant	32	2.5
Aggressiveness†
Less	873	66.7
More	435	33.3

^*Chi-square test

^‡Family history of cancer in a first-degree relative

^±Serum PSA at diagnosis for cases and at interview for controls

^†Less aggressive: localized stage, Gleason score ≤7 (3+4), and a diagnostic PSA level <20 ng/mL; More aggressive: regional or distant stage, or Gleason score ≥7 (4+3) or a diagnostic PSA level ≥20 ng/mL