Table 2.

List of genetic variations in circadian genes included in the analysis

dbSNP ID	Gene	SNP Typea	Allele (Major/Minor)	MAF	P for HWE	Location
rs2278749	ARNTL	Tagging	G/A	0.184	0.320	11p15
rs2290035	ARNTL	Tagging	A/T	0.457	0.227	11p15
rs3816360	ARNTL	Tagging	G/A	0.353	0.706	11p15
rs4757144	ARNTL	Tagging	A/G	0.409	0.901	11p15
rs6486122	ARNTL	Tagging	T/C	0.335	0.810	11p15
rs7950226	ARNTL	Tagging	G/A	0.457	0.356	11p15
rs11133373	CLOCK	Tagging	C/G	0.341	0.162	4q12
rs11133376	CLOCK	Tagging	T/C	0.462	0.000	4q12
rs1399953	CLOCK	Tagging	G/A	0.266	0.850	4q12
rs17776421	CLOCK	Tagging	G/A	0.383	0.776	4q12
rs10778528	CRY1	Tagging	T/G	0.430	0.650	12q23-q24.1
rs10778534	CRY1	Tagging	T/C	0.362	0.063	12q23-q24.1
rs12315175	CRY1	Tagging	T/C	0.194	0.954	12q23-q24.1
rs7297614	CRY1	CGEMS	T/C	0.392	0.759	12q23-q24.1
rs11605924	CRY2	Tagging	A/C	0.472	0.035	11p11.2
rs12281674	CRY2	Tagging	A/G	0.030	0.893	11p11.2
rs2292910	CRY2	Tagging	C/A	0.316	0.245	11p11.2
rs2292912	CRY2	Tagging	C/G	0.217	0.619	11p11.2
rs135757	CSNK1E	CGEMS	G/A	0.245	0.160	22q13.1
rs1534891	CSNK1E	CGEMS	C/T	0.124	0.001	22q13.1
rs1997644	CSNK1E	Tagging	A/G	0.467	0.039	22q13.1
rs5757037	CSNK1E	Tagging	G/A	0.369	0.039	22q13.1
rs6001093	CSNK1E	CGEMS	T/C	0.184	0.172	22q13.1
rs1369481	NPAS2	Tagging	G/A	0.300	0.315	2q11.2
rs1562313	NPAS2	CGEMS	G/A	0.208	0.782	2q11.2
rs17024926	NPAS2	Tagging	T/C	0.329	0.504	2q11.2
rs2305160	NPAS2	AA change	C/T	0.340	0.418	2q11.2
rs4074920	NPAS2	Tagging	A/G	0.245	0.041	2q11.2
rs7565018	NPAS2	Tagging	A/G	0.236	0.725	2q11.2
rs895521	NPAS2	CGEMS	G/A	0.240	0.258	2q11.2
rs965519	NPAS2	Tagging	A/G	0.153	0.657	2q11.2
rs2253820	PER1	Tagging	G/A	0.154	0.881	17p13.1-p12
rs2289591	PER1	Tagging	G/T	0.243	0.495	17p13.1-p12
rs885747	PER1	Tagging	C/G	0.456	0.983	17p13.1-p12
rs11695472	PER2	Tagging	A/C	0.269	0.072	2q37.3
rs7602358	PER2	Tagging	T/G	0.238	0.221	2q37.3
rs1012477	PER3	Tagging	C/G	0.143	0.179	1p36.23
rs10462020	PER3	AA change	T/G	0.192	0.120	1p36.23
rs11121023	PER3	Tagging	G/A	0.219	0.584	1p36.23
rs228697	PER3	AA change	C/G	0.099	0.781	1p36.23
rs2640909	PER3	AA change	T/C	0.295	0.327	1p36.23
rs2291739	TIMELESS	AA change	T/C	0.411	0.002	12q12-q13
rs774027	TIMELESS	AA change	T/A	0.453	0.456	12q12-q13
rs774047	TIMELESS	AA change	C/T	0.451	0.511	12q12-q13

^aAA = amino acid, CGEMS = Cancer Genetic Markers of Susceptibility