TABLE 1.
Hepatic and intestinal lipid concentrations in WT and Tis7−/− mice fed a high-fat diet for 8 wk (Expt. 1)1
| Cholesterol, μmol/g |
Triglycerides, μmol/g |
FFA, nmol/g |
Phospholipids, μmol/g |
|||||
| WT | Tis7−/− | WT | Tis7−/− | WT | Tis7−/− | WT | Tis7−/− | |
| Liver | 2.58 ± 0.59 | 0.75 ± 0.31* | 8.24 ± 0.44 | 2.03 ± 0.50* | 2.10 ± 0.17 | 1.07 ± 0.13* | 4.14 ± 0.33 | 4.00 ± 0.28 |
| Proximal intestine | 1.22 ± 0.10 | 0.84 ± 0.08* | 40.79 ± 8.46 | 19.15 ± 4.60* | 21.73 ± 6.53 | 12.14 ± 3.29 | 3.07 ± 0.26 | 2.65 ± 0.13 |
| Distal intestine | 1.81 ± 0.17 | 1.79 ± 0.29 | 790.10 ± 84.20 | 930.59 ± 200.74 | 44.99 ± 7.02 | 92.18 ± 16.71* | 1.76 ± 0.15 | 1.88 ± 0.32 |
1
Values are means ± SEM. For liver lipids, = 5 (Tis7−/− and WT); for proximal intestine, n = 5 (Tis7−/−) or 4 (WT); for distal intestine, n = 5 (Tis7−/− and WT) except triglycerides, n = 4 (Tis7−/− and WT). *Different from WT, P < 0.05.