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. 2009 Dec 4;69(2):91–103. doi: 10.1159/000264447

Table 2.

. Empirical results for different strategies using the haplotype frequencies from the CAMP data with 682 trios

Strategy β FBAT-C Linear
FBAT-C Robust
Bonferroni
exactly all DSLs at least one DSL only non-DSL markers exactly all DSLs at least one DSL only non-DSL markers exactly all DSLs at least one DSL only non-DSL markers
1 DSLa 0.25 0.396 0.032 0.150 0.392 0.112 0.150 0.238 0.028 0.040
0.5 0.832 0.082 0.084 0.814 0.194 0.104 0.118 0.078 0.000

2 DSLa 0.25 0.242 0.470 0.052 0.116 0.540 0.084 0.026 0.646 0.000
0.5 0.672 0.300 0.000 0.450 0.362 0.028 0.088 0.794 0.004

Untyped DSLb 0.25 0.372 0.058 0.064 0.354 0.056 0.066 0.352 0.166 0.046
0.5 0.834 0.162 0.002 0.846 0.132 0.016 0.254 0.744 0.002

When the true model is one DSL, the column ‘at least one DSL’ indicates the case when the DSL is found and additional non-DSL markers are found. When the true model is two DSLs the column ‘at least one DSL’ included the case when only one of the two DSL markers is found, with or without any additional markers. The columns for each strategy do not sum to 1, as the case when no markers are found is not included in the table.

a

For 1 and 2 DSLs, random markers were chosen as the DSL(s).

b

For the untyped DSL, rs1800872 was chosen as the DSL, but was omitted from the marker set, and rs1800871 was considered to be ‘the true DSL’ because of the high correlation (0.93). Based on 500 simulations; approximate SE <0.01.