Table 5.
Type I error rates (in percentage) for HST.P and HST-MLB.P to identify SNP pairs that partially explain the IBD sharing at the linkage peak evaluated at a 5% significance level using 9,000 replicates
| Model | Additive | Dominant | Multiplicative | Recessive | ||||
|---|---|---|---|---|---|---|---|---|
| P(hD) | 0.1 | 0.2 | 0.1 | 0.2 | 0.2 | 0.3 | 0.2 | 0.3 |
| HST.P | 5.2 | 5.2 | 4.6 | 5.0 | 4.4 | 4.7 | 4.9 | 5.1 |
| HSTMLB.P | 5.2 | 5.2 | 4.6 | 5.0 | 4.4 | 4.7 | 4.9 | 5.1 |
P(hD) is the risk haplotype frequency. The approximate 95% confidence intervals of the type I error rate that do not contain 0.05 are bolded.