Table 3.

Histocompatibility profile and antibody specificity of high PRA recipients

Patient	HLA recipient			Current	Current	Antibody	HLA donor
number				crossmatch	PRA	specificity^a
	A	B	DR				A	B	DR
4	2, –	51, 57	2, –	Positive	94	Undefined	1, –	8, 35	3, 5
6	25, 32	18, 44	4, 6	Positive	20	Weak P02	1, 2	8, 51	3, 5
7	2, 24	7, 27	8, –	Positive	91	Undefined	1, 2	8, 57	3, 7
9	1, 2	35, –	4, 5	Negative	20	A10	1, –	7, –	7, –
11	24, –	44, –	5, 6	Positive	64	P02 + ?	1, 24	35, 57	6, 7
13	3, –	7, 35	2, –	Negative	26	Undefined	2, –	7, 51	2, 5
15	2, 29	7, 44	6, 7	Negative	29	Undefined	2, 28	14, 62	5, 6
16	26, 31	14, 35	1, –	Negative	14	B17	2, 11	7, 35	6, 8
22	2, 28	7, 62	2, 4	Positive	98	P81 + P71	3, –	7, 60	2, 6
24	32, –	18, 53	5, 7	Negative	0	A2^b	2, 29	7, 49	1, 6
28	24, 33	58, 60	ND	Positive	84	B12, B7, B22	2, 29	44, 50	4, 7
35	11, 32	35, 44	7, –	Negative	13	Weak A2	26, 36	53, 58	4, 7
38	30, 31	38, 51	7, –	Negative	28	A3	2, 31	60, –	4, 13

Private and public specificities were determined by panel cell analysis using a χ² tailed analysis as previously described.¹³ Public specificities are defined as follows: P02 = A2, A28; P81 = A9, A32, Bw4; P71 = A1, A3, A9, A10, A11.

Specificity of historic serum, which was crossmatch positive. Current serum was crossmatch negative.

ND, not determined.

Underlined antigens indicate those included in the defined antibody specificities.