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. 2010 Sep 20;11(9):3397–3412. doi: 10.3390/ijms11093397

Figure 2.

Figure 2

Scoring multiple toxicological endpoints using toxicogenomics data. Multiple toxicological endpoint-associated gene sets or TGx biomarkers need to be prepared in advance, and the overall expression changing levels for each gene set are calculated by certain algorithms such as the D-score, by which affected levels for each biological pathway can be evaluated intuitively.