Table 1.
Participant characteristics
| Variables | African-Americans (n = 1,037) | Non-Hispanic Whites (n = 882) | p Value* |
|---|---|---|---|
| Age (yrs) | 64.8 ± 8.6 | 61.1 ± 9.3 | <0.001 |
| Women | 751 (72%) | 492 (56%) | <0.001 |
| Body mass index (kg/m2) | 32.0 ± 6.6 | 31.4 ± 6.3 | 0.008 |
| Total cholesterol (mg/dl) | 201.5 ± 41.7 | 196.6 ± 33.6 | 0.004 |
| HDL cholesterol (mg/dl) | 57.6 ± 17.8 | 50.7 ± 14.7 | <0.001 |
| Plasma glucose level (mg/dl) | 115.6 ± 51.0 | 107.9 ± 26.3 | <0.001 |
| Systolic BP (mm Hg) | 142.3 ± 20.8 | 135.3 ± 17.1 | <0.001 |
| Diastolic BP (mm Hg) | 79.9 ± 11.4 | 74.6 ± 9.7 | <0.001 |
| Heart rate (beats/min) | 68 ± 12 | 65 ± 11 | 0.001 |
| Serum creatinine (mg/dl) | 0.91 ± 0.33 | 0.91 ± 0.26 | NS |
| eGFR (ml/min) | 97.9 ± 31.2 | 83.3 ± 22.8 | <0.001 |
| Ever-smoker | 420 (40%) | 431 (49%) | <0.001 |
| Diabetes mellitus | 348 (34%) | 160 (18%) | <0.001 |
| Previous myocardial infarction or stroke | 138 (13%) | 122 (14%) | NS |
| β blocker | 213 (20%) | 375 (42%) | <0.001 |
| Calcium channel blocker | 367 (35%) | 174 (20%) | <0.001 |
| Diuretic | 587 (57%) | 447 (51%) | 0.004 |
| Renin-angiotensin-aldosterone system inhibitors | 508 (49%) | 420 (48%) | NS |
| Statin | 222 (21%) | 307 (35%) | <0.001 |
| Aspirin | 371 (36%) | 432 (49%) | 0.003 |
| MR-proANP (pmol/L) | 62.5 (43.8–93.1) | 63.1 (44.0–95.0) | 0.35 |
Continuous variables are presented as mean ± SD or median (interquartile range), and categorical variables are presented as numbers (percentages).
*
For ethnic differences after adjustment for age and gender.
eGFR = estimated glomerular filtration rate; HDL = high-density lipoprotein.