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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: J Mol Cell Cardiol. 2010 Aug 6;49(5):801–811. doi: 10.1016/j.yjmcc.2010.08.002

Figure 5. Ventricular remodeling following MI was characterized by myocyte lengthening in males but cross-sectional growth in females.

Figure 5

(A) Sixty days following MI (small infarcts), body weights were recorded, mice were euthanized, heart weight was measured, and HW/BW calculated. (B–D). Cardiac myocytes (MC) were isolated and myocyte volume was determined using a Coulter Channelyzer. Myocyte length was determined microscopically (40 cells/sample). Short axis length was then calculated assuming an ellipsoid cross-section. Data are presented as mean ± SEM for the number of mice shown in A (male, black bars; female, white bars). Groups were compared by two-way ANOVA with Bonferroni post-test to determine the contribution of sex or infarct size.

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