Table 2.

Base-case parameters for the two-state, allosteric catch-bond model of FimH-mannose bond

Parameter	Value
$k_{10}^0$ ∗	>6 s−1
$k_{20}^0$	5.10×10−6 s−1
$k_{21}^0$	0.025 s−1
$k_{12}^0$	0.00125 s−1
$k_{01}^0$ ∗	>3 s−1
$k_{02}^0$	<1e-6
x10	4.52 Å
x20	4.52 Å
x12	12 Å
x21	−12 Å

Origins of other parameters are described in the Supporting Material.

^∗Parameters were varied in simulations.