FIGURE 6.

MCp recruitment to the lung is significantly reduced in sensitized and Ag-challenged CCL2- and CCR2-deficient mice. Average concentration of MCps in individual mouse lungs (MCps/106 MNCs) (A) and number of lung MNCs recovered per mouse (B) from OVA-sensitized WT and CCL2−/− mice with and without aerosolized OVA challenges. Values are the mean ± SEM from three separate experiments. Average concentration of MCps in individual mouse lungs (MCps/106 MNCs) (C) and number of lung MNCs recovered per mouse (D) from OVA-sensitized WT and CCR2−/− mice with and without aerosolized OVA challenges. Values are the mean ± SEM from four separate experiments. *p < 0.05, two-tailed Student t test.