FIG. 4.

Expression of cyclooxygenase-2 (COX-2) in mice treated with RvE1. Corneas were obtained after 14 days of DE conditions and treatment with drug and vehicle for the last 7 days. (A) Western blot analysis shows a 78 kDa band corresponding to COX-2. Values correspond to average ± SEM of 3 different experiments. (B) Immunostaining with a COX-2 antibody. The nuclei were counterstained with 4,6-diamidino-2-phenylindole. *Significant differences versus DE. Color images available online at www.liebertonline.com/jop.