. Author manuscript; available in PMC: 2010 Oct 18.

Published in final edited form as: J Biol Chem. 2006 Nov 15;282(3):1925–1937. doi: 10.1074/jbc.M610602200

TABLE 2. Physiologic and pathologic analysis of control and ethanol-treated animals indicating the mild pathology associated with this model of early ALD.

Comparison of serum alanine aminotransferase (ALT) levels, ammonia levels, and the liver to body weight ratios between control and ethanol-treated animals indicate a moderate yet significant increase in all parameters following ethanol exposure (1.8-, 1.28-, and 2.34-fold over control). These increases indicate mild liver damage associated with the model of ALD used here.

Treatment	ALT	Ammonia	Body weight	Liver weight	Liver/body ratio
	units/liter	μm	g	g
Control	19 ± 3	176.7 ± 22	402.9 ± 11.9	11.5 ± 0.4	2.87 ± 0.08
Ethanol	35 ± 5^a	226.2 ± 23^a	315.3 ± 7.3^a	10.6 ± 0.5	6.73 ± 0.27^a

Values are p < 0.05, n = 16.