Table 3.
Treatment | TNF α | TGF β | IL-1 β | IL-4 | Il-6 |
---|---|---|---|---|---|
Control | 0.8 ± 0.2 | 0.3 ± 0.1 | 1.2 ± 0.1 | 0.59 ± 0.14 | 10 ± 2 |
Control + NAC | 0.8 ± 0.2 | 0.3 ± 0.1 | 1.3 ± 0.2 | 0.42 ± 0.16 | 4 ± 1# |
EtOH | 4.3 ± 1.3* | 1.2 ± 0.2* | 1.4 ± 0.2 | 0.20 ± 0.02* | 10 ± 1 |
EtOH + NAC | 2.4 ± 0.3* | 1.0 ± 0.2* | 1.4 ± 0.3 | 0.15 ± 0.03* | 8 ± 2 |
Data are presented as means ± SE for mRNA transcript expression normalized to expression of the housekeeping gene cyclophilin for N = 8 –13 rats/group.
Statistically significant P < 0.05 EtOH vs respective controls.
Statistically significant P < 0.05 vs control by two-way ANOVA followed by Student’s Neuman-Keuls post hoc analysis.