Skip to main content
. Author manuscript; available in PMC: 2010 Oct 18.
Published in final edited form as: Nat Genet. 2010 Feb 7;42(3):216–223. doi: 10.1038/ng.527

Figure 7. Lung tumorigenesis in Dok2 +/− mice.

Figure 7

(a) Summary of lung tumor incidence in Dok2 +/− mice (n = 12) and wild-type controls (n = 13) at 15–19 months of age. *, P < 0.05 by two-tailed Fisher’s exact test. (b) PCR analysis of genomic DNA from tail DNA (top panel) or laser capture microdissected-lung cells (bottom panel) in four Dok2 +/− mice (#1–4). Tumor cells (T) or normal adjacent lung (N) on the same slide was microdissected and then used for DNA extraction and PCR analysis with Dok2 genotyping primers that distinguish between the KO allele (upper band) and wild-type allele (lower band).