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. Author manuscript; available in PMC: 2011 Sep 28.
Published in final edited form as: Circulation. 2010 Sep 13;122(13):1308–1318. doi: 10.1161/CIRCULATIONAHA.110.964684

Figure 6.

Figure 6

Luciferase-reporter assays showed that ROCK1, PTEN, CAMKIIδ, FGFR2, and LIF were authentic targets of miR-494; however, Api5 was a false target of miR-494, albeit predicted by Target-Scan software. β-gal was used as transfection control. Similar results were observed in three additional, independent experiments (*, p< 0.003 versus miR mimic controls). Luc=plasmid luciferase; Luc-R3=plasmid Luc-ROCK1-3UTR; Luc-R3M= plasmid Luc-ROCK1-3UTR mutant; and so on.