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IFNG mRNA expression in unstimulated PB compared to LP T cells. (A) IFNG mRNA as determined by real-time PCR in PB T cells versus LP T cells. (B) Correlation of IFNG mRNA levels to methylation status of the CNS-22, promoter, and transcribed IFNG CpG regions for PB T and LP T cells. Spearman's correlation coefficient is −0.06 (P < 0.001) for the promoter and 0.14 (P < 0.04) for the transcribed regions.
