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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Bioorg Med Chem Lett. 2010 Aug 21;20(21):6306–6309. doi: 10.1016/j.bmcl.2010.08.076

Table 1.

Enzyme inhibition data for 1,4-benzoxazines identified in the high-throughput screen.a

Compound % inhibition of MenB
at 125 µg/ml
1482I15 68.4±7.3
1486C16 98.0±1.2
1615I20 60.3±10.3
1515O10 77.3±5.2
a

MenB concentration was 150 nM and OSB concentration was 30 µM.