Skip to main content
. Author manuscript; available in PMC: 2010 Oct 18.
Published in final edited form as: Arch Dermatol. 2008 Jul;144(7):851–858. doi: 10.1001/archderm.144.7.851

Figure 3.

Figure 3

Refractory antifibrotic responses with repetitive high-dose UV-A1 irradiation. Eight healthy subjects with lightly pigmented skin (L* [luminescence] >65) were treated with high-dose UV-A1 irradiation (110 J/cm2) either once (Friday) or 3 times (Monday, Wednesday, and Friday). Four days later (the following Tuesday), all biopsy samples were collected and assessed by real-time polymerase chain reaction for the indicated transcripts: type I and type III procollagen (A) and matrix metalloproteinases (MMPs) 1, 3, and 9 (B). Data are presented as mean fold change relative to untreated skin (normalized to 1). Error bars represent SEM. In A, the horizontal dashed line indicates fold change of untreated skin. *P<.05 compared with untreated skin. mRNA indicates messenger RNA.