Table 3.
Adipocyte measurements and fatty acid uptake kinetics
| Group | Diameter (μm) | Surface area per cell (μm)2 | Volume per cell (pL) | Vmax (pmol/s/50,000 cells) | Km (nM) | k (ml/s/50,000 cells) | Vmax/SA×108 (pmol/s/μ2) |
|---|---|---|---|---|---|---|---|
| Cohort 1 | |||||||
| Obese | 94.7±6.8** | 32,717±9,492**** | 486±191 | 19.6±4.7* | 149±15 | 0.0105±0.0055 | 1.20±0.45 |
| Control | 53.4±4.4 | 9,953±1,659 | 81±18 | 4.8±2.0 | 142±49 | 0.0068±0.0018 | 0.96±0.43 |
| Cohort 2 | |||||||
| Obese 2 | 101.6±4.4*** | 32,799±2,784*** | 568±71*** | ND | ND | ND | ND |
| Control 2 | 58.1±5.8 | 10,910±2,630 | 112±42 | ND | ND | ND | ND |
p < 0.05;
p < 0.01;
p < 0.001;
0.1 > p > 0.05 compared with cohort controls