Table 5.
Downregulated genes in oxidative phosphorylation pathway
| Gene | ID | EC | Complex | Fold change down |
|
|---|---|---|---|---|---|
| Cohort 1 | Cohort 2 | ||||
| NADH dehydrogenase (ubiquinone) Fe–S protein 7, 20 kDa (NADH–coenzyme Q reductase) | NDUFS7 | 1.6.5.3; 1.6.99.3 | I | 1.48 | 1.31 |
| Succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | SDHA | 1.3.5.1 | II | 1.40 | 1.16 |
| Cytochrome c-1 | CYC1 | 1.10.2.2 | III | 1.48 | 1.37 |
| Cytochrome c oxidase subunit IV isoform 1 | COX4I1 | 1.9.3.1 | IV | 1.51 | 1.11 |
| ATPase, H+ transporting, lysosomal 50/57 kDa, V1 subunit H | ATP6V1H | 3.6.3.14 | V | 1.55 | 1.24 |
| ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G | ATP5L | 3.6.1.14 | V | 1.35 | 1.37 |
| ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | ATP5D | 3.6.1.14 | V | 1.51 | 1.12 |