Table 5.
Effect of adoptive transfer of splenic lymphocytes from FK506-treated LEW rats with ACI liver grafts on the acceptance of ACI livers by naive LEW recipients
| Group | Splenocyte donor |
Num- ber of cells (×10a) |
n | Graft survival (days) |
MST (days) |
Pa |
|---|---|---|---|---|---|---|
| 1 | — | — | 10 | 9, 9, 9, 9, 10, 10, 10, 11, 12, 13 |
10.0 | — |
| 2 | Normal LEW | 200 | 5 | 9, 9, 9, 10, 10 | 9.0 | NS |
| 3 | FK-treated LEW with ACI liver graft (100 days)b |
200 | 7 | 8, 8, 10, 10, 11, 12, 12 | 10.0 | NS |
| 4 | FK-treated LEW with ACI liver graft (300 days)b |
200 | 4 | 9, 10, 10, 11 | 10.0 | NS |
a
Wilcoxon rank sum test.
b
Splenocytes were pooled from 4 and 2 animals, each of which had functioning liver grafts for 100 and more than 300 days.