Table 1.
Characteristics of Females and Matched Males with SCCHN.
| Females (n = 286) |
Males (n = 286) |
||||
|---|---|---|---|---|---|
| Variable | N | (%) | N | (%) | P Value |
| Age* category | .788 | ||||
| < 50 years | 76 | (26.6) | 69 | (24.1) | |
| 50–69 years | 172 | (60.1) | 179 | (62.6) | |
| ≥ 70 years | 38 | (13.3) | 38 | (13.3) | |
| Race/ethnicity* | 1.0 | ||||
| White, Anglo, Caucasian | 264 | (92.3) | 264 | (92.3) | |
| Spanish origin | 10 | (3.5) | 10 | (3.5) | |
| African American | 12 | (7.7) | 12 | (7.7) | |
| Adult comorbidity classification | .078 | ||||
| None or mild | 257 | (89.9) | 243 | (85.0) | |
| Moderate or severe | 29 | (10.1) | 43 | (15.0) | |
| Smoking status* | .980 | ||||
| Current smoker | 140 | (49.0) | 142 | (49.7) | |
| Former smoker | 75 | (26.2) | 73 | (25.5) | |
| Never smoker | 71 | (24.8) | 71 | (24.8) | |
| Alcohol drinking status | <.001 | ||||
| Current drinker | 110 | (38.5) | 162 | (56.6) | |
| Former drinker | 50 | (17.5) | 71 | (24.8) | |
| Never drinker | 126 | (44.1) | 53 | (18.5) | |
| Marital status† | .002 | ||||
| Married | 185 | (66.6) | 215 | (77.9) | |
| Widowed, divorced, or separated | 81 | (29.1) | 46 | (16.7) | |
| Never married | 12 | (4.3) | 15 | (5.4) | |
| Educational level attained† | .840 | ||||
| < High school | 37 | (13.3) | 34 | (12.4) | |
| High School, technichal or vocational school, or assoceate degree or some college | 161 | (57.9) | 166 | (60.3) | |
| Bachelor's degree or advanced degree | 80 | (28.8) | 75 | (27.3) | |
| Income level† | .281 | ||||
| < $25,000 | 75 | (27.8) | 59 | (22.0) | |
| $25,000–74,999 | 112 | (41.5) | 116 | (43.3) | |
| ≥ $75,000 | 83 | (30.7) | 93 | (34.7) | |
| Tumor site* | 1.0 | ||||
| Oral cavity | 132 | (46.2) | 132 | (46.2) | |
| Oral tongue or floor of mouth | 88 | 88 | |||
| Gingivobuccal^ | 44 | 44 | |||
| Oropharynx | 92 | (32.2) | 92 | (32.2) | |
| Tonsil | 48 | 43 | |||
| Other oropharynx | 44 | 49 | |||
| Larynx | 55 | (19.2) | 55 | (19.2) | |
| Supraglottic | 43 | 34 | |||
| Glottic | 12 | 21 | |||
| Hypopharynx | 7 | (2.4) | 7 | (2.4) | |
| Tumor classification* | .992 | ||||
| T1 | 77 | (26.9) | 74 | (25.9) | |
| T2 | 104 | (36.4) | 107 | (37.4) | |
| T3 | 55 | (19.2) | 55 | (19.2) | |
| T4 | 50 | (17.5) | 50 | (17.5) | |
| Nodal classification* | .247 | ||||
| N0 | 140 | (49.0) | 140 | (49.0) | |
| N1 | 49 | (17.1) | 34 | (11.9) | |
| N2 | 89 | (31.1) | 105 | (36.7) | |
| N3 | 8 | (2.8) | 7 | (2.4) | |
| Stage | .621 | ||||
| I | 56 | (19.6) | 54 | (18.9) | |
| II | 54 | (18.9) | 56 | (19.6) | |
| III | 55 | (19.2) | 44 | (15.4) | |
| IV | 121 | (42.3) | 132 | (46.2) | |
| Grade# | .995 | ||||
| Well differentiated | 34 | (11.9) | 34 | (11.9) | |
| Moderately differentiated | 140 | (49.0) | 141 | (49.3) | |
| Poorly differentiated | 76 | (26.6) | 75 | (26.2) | |
| Treatment* | 1.0 | ||||
| Surgery alone | 85 | (29.7) | 85 | (29.7) | |
| Surgery + radiotherapy | 45 | (15.7) | 45 | (15.7) | |
| Surgery + chemotherapy | 1 | (0.3) | 1 | (0.3) | |
| Surgery + chemoradiotherapy | 21 | (7.3) | 21 | (7.3) | |
| Radiotherapy alone | 64 | (22.4) | 64 | (22.4) | |
| Chemoradiotherapy | 70 | (24.5) | 70 | (24.5) | |
*
Matched variables (age, ± 10 years; race/ethnicity, smoking status, ever versus never; tumor site, oral cavity versus oropharynx versus larynx versus hypopharynx; tumor classification, T1–2 versus T3–4; nodal classification, N0 versus N1–3; and treatment).
†
Missing data: 8 women and 10 men for marital status; 8 women and 11 men for education level attained; 16 women and 18 men for income level.
#
Grade was not recorded in 36 females and 36 males.
^
One female and the corresponding matched male had a primary tumor of the mandibular gingiva and a simultaneous second primary tumor of the oropharynx.