Table 3. Hazard Ratio (95% CI) of incident T2D by tertiles of total WBC and sub-fractions.
| Lowest tertile | Middle tertile | Highest tertile | P for trend | |
| WBC (n) | 5,477 | 5,120 | 4,953 | |
| Mean 103 cells L−1 | 4.9 | 6.4 | 8.5 | |
| Diabetes (n) | 111 | 160 | 228 | |
| Range | ≤5.7 | 5.8–7.0 | ≥7.1 | |
| Model 1 | 1 | 1.47 (1.17–1.90) | 2.19 (1.74–2.75) | <0.001 |
| Model 2 | 1 | 1.33 (1.04–1.70) | 1.82 (1.45–2.29) | <0.001 |
| Granulocytes (n) | 5,499 | 4,940 | 5,111 | |
| Mean 103 cells L−1 | 2.7 | 3.8 | 5.5 | |
| Diabetes (n) | 131 | 155 | 213 | |
| Range | ≤3.3 | 3.4–4.3 | ≥4.4 | |
| Model 1 | 1 | 1.28 (1.01–1.61) | 1.68 (1.35–2.08) | <0.001 |
| Model 2 | 1 | 1.14 (0.90–1.43) | 1.45 (1.17–1.81) | 0.001 |
| Lymphocytes (n) | 5,646 | 5,319 | 4,585 | |
| Mean 103 cells L−1 | 1.44 | 1.97 | 2.78 | |
| Diabetes (n) | 134 | 151 | 214 | |
| Range | ≤1.7 | 1.8–2.2 | ≥2.3 | |
| Model 1 | 1 | 1.21 (0.96–1.53) | 2.02 (1.63–2.51) | <0.001 |
| Model 2 | 1 | 1.09 (0.86–1.37) | 1.66 (1.33–2.06) | <0.001 |
| Monocytes (n) | 5,754 | 5,899 | 3,897 | |
| Mean 103 cells L−1 | 0.23 | 0.48 | 1.00 | |
| Diabetes (n) | 156 | 199 | 144 | |
| Range | ≤0.3 | 0.4–0.6 | ≥0.7 | |
| Model 1 | 1 | 1.17 (0.94–1.44) | 1.22 (0.97–1.54) | 0.07 |
| Model 2 | 1 | 1.10 (0.90–1.36) | 1.14(0.90–1.42) | 0.268 |
Model 1: adjusted for age and sex (n = 15,550).
Model 2: as model 1 plus smoking status, family history of diabetes, physical activity level, education level, BMI and waist circumference (n = 15,550).