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. 2010 Oct 18;5(10):e13452. doi: 10.1371/journal.pone.0013452

Figure 4. Striatal signaling effects of 3-MT are reduced in TAAR1-KO mice.

Figure 4

Effect of 3-MT infusion (18 µg, 30 min after treatment) on Erk2 (A) and CREB (B) phosphorylation in WT and TAAR1-KO mice. 3-MT induced significant phosphorylation of both Erk2 and CREB in WT mice, but not in TAAR1-KO mice (* p<0.05; Student's t-test n = 10 per group).