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Western blot analysis of ADAM-10 in retina tissue from (a) control and STZ induced diabetic mice (b) control and intravitreal VEGF injected mice and (c) human retinas from patients with no diabetes, diabetes or diabetes with diabetic retinopathy(d) Densitometric quantitation of mature ADAM-10 (mADAM-10) relative to actin on the same blot. ** p≤0.03.
