Figure 3.

Analysis of graft-infiltrating T cells. Activated CD25⁺ T cells and CD4⁺ and CD8⁺ T cell subsets were stained at the time points of corneal allograft rejection and calculated within the graft. A, C, and E show representative histological staining for CD25, CD4, and CD8 in grafts of treated and control animals, respectively. CD25⁺ (B) and CD4⁺ (D) cells infiltrated to a statistically significantly stronger extent in 3.2.3-treated animals when compared to control treated animals (*p<0.01, ** p<0.01). No statistical difference was observed for CD8⁺ T cells (NS=not significant; F).