Table 1. Allele frequencies of HLA-DRB1 in Japanese patients with normal tension glaucoma.
|
|
Frequency, n (%) |
|
|
|
|---|---|---|---|---|
| HLA-DRB1 | Cases (n=113) | Controls (n=184) | p | pc |
| 0101 |
17 (7.5) |
20 (5.4) |
0.38 |
|
| 0301 |
0 (0.0) |
1 (0.3) |
1 |
|
| 0401 |
0 (0.0) |
1 (0.3) |
1 |
|
| 0403 |
6 (2.7) |
12 (3.3) |
0.81 |
|
| 0405 |
27 (11.9) |
43 (11.7) |
1 |
|
| 0406 |
5 (2.2) |
11 (3.0) |
0.79 |
|
| 0407 |
1 (0.4) |
3 (0.8) |
1 |
|
| 0410 |
8 (3.5) |
7 (1.9) |
0.28 |
|
| 0802 |
12 (5.3) |
23 (6.3) |
0.72 |
|
| 0803 |
15 (6.6) |
30 (8.2) |
0.53 |
|
| 0901 |
30 (13.3) |
54 (14.7) |
0.72 |
|
| 1001 |
2 (0.9) |
0 (0.0) |
0.14 |
|
| 1101 |
5 (2.2) |
8 (2.2) |
1 |
|
| 1201 |
9 (4.0) |
12 (3.3) |
0.65 |
|
| 1202 |
7 (3.1) |
8 (2.2) |
0.59 |
|
| 1301 |
5 (2.2) |
1 (0.3) |
0.032 |
NS |
| 1302 |
16 (7.1) |
28 (7.6) |
0.87 |
|
| 1303 |
0 (0.0) |
1 (0.3) |
1 |
|
| 1307 |
0 (0.0) |
1 (0.3) |
1 |
|
| 1401 |
7 (3.1) |
13 (3.5) |
1 |
|
| 1403 |
1 (0.4) |
5 (1.4) |
0.42 |
|
| 1405 |
2 (0.9) |
7 (1.9) |
0.49 |
|
| 1406 |
4 (1.8) |
3 (0.8) |
0.44 |
|
| 1412 |
0 (0.0) |
1 (0.3) |
1 |
|
| 1501 |
17 (7.5) |
23 (6.3) |
0.61 |
|
| 1502 |
28 (12.4) |
48 (13.0) |
0.90 |
|
| 1602 | 2 (0.9) | 4 (1.1) | 1 | |