Table 3. Frequencies of DRB1-DQB1 haplotypes in Japanese patients with normal tension glaucoma (NTG).
|
|
Frequency, n (%) |
|
|
|
|---|---|---|---|---|
| Haplotype* | Cases (n=113) | Controls (n=184) | p | pc |
| DRB1*0901:DQB1*0303 |
29 (12.8) |
53 (14.4) |
0.63 |
|
| DRB1*1502:DQB1*0601 |
28 (12.4) |
47 (12.8) |
1 |
|
| DRB1*0405:DQB1*0401 |
26 (11.5) |
40 (10.9) |
0.89 |
|
| DRB1*1302:DQB1*0604 |
16 (7.1) |
28 (7.6) |
0.87 |
|
| DRB1*0803:DQB1*0601 |
14 (6.2) |
29 (7.9) |
0.52 |
|
| DRB1*0101:DQB1*0501 |
17 (7.5) |
20 (5.4) |
0.38 |
|
| DRB1*1501:DQB1*0602 |
14 (6.2) |
19 (5.2) |
0.59 |
|
| DRB1*1301:DQB1*0603 | 5 (2.2) | 1 (0.3) | 0.032 | NS |
*Only haplotypes that reached frequencies >5% in all subjects or that may have an effect on the development of NTG are shown.