Table 1.

Schedule of measurements.

	S	6	12	18	24	30	36	42	48	54	60
		m	m	m	m	m	m	m	m	m	m
History/events	X	X	X	X	X	X	X	X	X	X	X
Physical examination	X		X		X		X		X		X
Symptom assessment	X	X	X	X	X	X	X	X	X	X	X
Routine laboratory	X	X	X		X		X		X		X
Electrocardiography	X	X	X		X		X		X		X
Echocardiography	X		X		X		X		X		X
Stress MPI	X						X				X
Medications	X	X	X	X	X	X	X	X	X	X	X
Angiograms	X										X
CAC-Scan	X										X
Arterial stiffness	X										X
Resources utilization											X
Quality of life	X										X
Work status	X										X
Serious adverse events			Continuous								X

Abbreviations: S = baseline; 6m = 6 month after study entry; 12 m to 60 m denotes months after study entry. Stress MPI=Stress myocardial perfusion imaging, CAC-Scan=Coronary-artery calcium (CAC) scan