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. 2010 Sep 26;8:88. doi: 10.1186/1479-5876-8-88

Table 2.

Summarized Body Weight, Heart Weight, Left Lung Weight and Heart Function in Studied Animals

Variables Group 1† (n = 8) Group 2† (n = 8) Group 3† (n = 8) Group 4† (n = 8) Group 5† (n = 8) p value*
Initial body weight (g) 328 ± 15.9 323 ± 11.8 323 ± 12.6 317 ± 24.3 325 ± 25.8 0.792
Final body weight (g) 450.0 ± 35.7 468.9 ± 26.4 476.5 ± 25.9 446.0 ± 29.9 465.7 ± 59.0 0.498
Final left lung weight (g) 1.70a ± 0.09 2.01b ± 0.15 1.76a ± 0.16 1.78a ± 0..21 1.78a ± 0.08 0.0009
Final heart weight (g) 1.46a ± 0.11 1.80b ± 0.24 1.55a,b ± 0.24 1.51a,b ± 0.28 1.42a ± 0.26 0.023
Day 0 LVEF (%) 79.3 ± 2.0 79.3 ± 3.5 80.9 ± 2.3 79.3 ± 3.2 80.9 ± 4.7 0.744
Day-30 LVEF (%) 79.8a ± 2.5 72.1b ± 1.7 74.8a,b ± 3.2 75.9a,b ± 5.0 78.7a ± 4.0 0.0005
Day-90 LVEF (%) 79.1a ± 3.3 70.2b ± 2.3 74.3a,b ± 0.6 74.5a,b± 3.8 78.6a,b ± 3.0 < 0.0001
FASBP on day 90, mmHg 122 ± 26 116 ± 21 109 ± 19 103 ± 22 108 ± 21 0.213

*: by one-way ANOVA. Different superscript letters between the groups indicate significant difference (at 0.05 level) by Tukey's multiple comparison procedure.

†: Group 1 = normal control; Group 2 = DCM only; Group 3 = DCM plus ADMSC; Group 4 = DCM plus sildenafil; Group 5 = DCM plus combined sildenafil and ADMSC.

FABP = femoral arterial blood pressure; LVEF = left ventricular ejection fraction.