Table 3.
Chylomicron Retention Disease Follow-Up
| Early Follow-Up (Annual) | |
| Clinical | |
| Anthropometry | Weight and height to draw growth curve |
| Digestive | Appetite, diarrhea, abdominal distension, vomiting, hepatic size? |
| Neurological | Developmental retardation, areflexia, ataxia, dysarthria, deep proprioception loss, muscular weakness or pain, cramps? |
| Dietary counseling | Sufficient caloric intake, low fat diet (fat <30% total energy), EFA supplementation? |
| Biological | |
| Lipids | Total and LDL cholesterol, HDL-C, TG |
| Hepatic | AST, ALT, GGT, total bilirubin, alkaline phosphatase? |
| Vitamins | Plasma levels of vitamins A, D, E and K or INR (vit K deficiency) |
| Essential Fatty Acids | Deficiency induced by low fat diet? |
| Blood cell count | Anemia? |
| Delayed Follow-Up (every 3 years) | |
| 1) After the age of 10 years | |
| Hepatic | Ultranosonography (steatosis, portal hypertension, yearly), Elastometry Fibroscan®? (further studies are needed) |
| Neurological exam | Clinical, creatine kinase, electromyography |
| Ophthalmologic exam | Fundus, color vision, visual evoked potentials, electroretinography |
| Total body composition | Bone mineral content for whole body |
| 2) Adult age | |
| Echocardiography | Ejection fraction |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK, creatine kinase; EFA, essential fatty acids; GGT, gamma-glutamyltranspeptidase; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TG, triglycerides