Table 4.

Concordance of results of HC-II assay and PCR test for detection of HPV infection in oral sub mucous fibrosis (OSMF): a potentially malignant oral lesions^a

Hybrid Capture-II (HC-II)	HPV-16 E6 PCR		Total
	HPV-16 E6 Positive	HPV-16 E6 Negative
HC-II Positive	42 (77.78%)	15 (9.74%)	57 (100)
HC-II Negative	12 (22.22%)	139 (90.26%)	151 (100)
Total	54	154	208

^aCohen's kappa (λ) = 66.83% (95%CI 0.5533-0.7834); Sensitivity = 73.68% (95% CI: 0.6034-0.8446); Specificity = 92.05% (95% CI: 0.8653-0.9583); Pearson χ² p < 0.00.