Table 5.

Concordance of results of HC-II assay and PCR test for detection of HPV infection in oral squamous cell carcinoma (OSCC): a malignant oral lesions^a

Hybrid Capture-II (HC-II)	HPV-16 E6 PCR		Total
	HPV-16 E6 Positive	HPV-16 E6 Negative
HC-II Positive	61 (84.72%)	11 (15.28%)	72 (100)
HC-II Negative	09 (6.00%)	141 (94.00%)	150 (100)
Total	70	152	222

^aCohen's Kappa (λ) = 79.29 (95%CI 0.7067-0.8792); Sensitivity = 87.14% (95% CI: 0.7699-0.9395); Specificity = 92.76% (95% CI: 0.8742-0.9633); Pearson χ² p < 0.00.