. Author manuscript; available in PMC: 2011 Dec 1.

Published in final edited form as: Pharmacol Biochem Behav. 2010 Aug 21;97(2):249–255. doi: 10.1016/j.pbb.2010.08.006

Table 2.

Effect of ambroxol on motor function in the rat

	Pre-dose	Post-dose

Rotarod test (sec)
Vehicle	60 (0.0)	60 (0.0)
Ambroxol	60 (0.0)	60 (0.0)
BBB
Vehicle	9.9 (0.7)	9.4 (1.2)
Ambroxol	7.5 (1.2)	8.3 (0.7)

Rats were tested 1 hr following oral dosing. The latency to fall (sec) in uninjured rats in the rotatod test was measured. BBB locomotor scores were measured on a scale of 0–21 in SCI rats. Neither vehicle nor ambroxol affected performance in either test. Data are mean (S.E.M.), N = 4/group.