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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Exp Gerontol. 2010 Jul 1;45(11):834–841. doi: 10.1016/j.exger.2010.06.007

Figure 1. Age-related changes in DCs expression of TNF-α, IL-12 and IL-10.

Figure 1

Bone marrow progenitor cells were isolated from C57BL/6 mice (n = 4–5 mice), differentiated with GM-CSF for six days, and then stimulated with the indicated TLR agonist, individually or in combination. After 12 h, culture supernatants were collected, and cytokines levels were measured by ELISA. Samples were assayed in triplicate. Data represent the mean ± SEM from three experiments. *, statistically significant p≤0.05 (18.months vs. 2, 6, or 12 months).