Figure 2. Expression of CD80 and CD86 on DCs from young and old mice after TLR stimulation.
Bone marrow progenitor cells from 2 and 18 months old C57BL/6 mice were differentiated with GM-CSF for six days, and then stimulated with the indicated TLR agonist, individually or in combination. After 24 hours (A) CD80 or (B) CD86 was measured by flow cytometry after labeling with fluorescent antibodies. These are representative experiments. (CD80 n= 3, CD86 n= 4).