Table 1.

A comprehensive list of EMT involved in chemoresistance

Chemotherapeutic Drug	Characteristics	Cell or tissue	References
Cetuximab	Epithelial cell lines were significantly more susceptible to this agent.	Human hepatoma cells	(Fuchs et al., 2008)
Erlotinib	Epithelial gene signature is associated with sensitivity to erlotinib.	Human hepatoma cells; Lung cancer	(Yauch et al., 2005)
Gefitinib	Epithelial cell lines were found to be significantly more susceptible to this agent; gefitinib-resistant cancer cells became EMT-type cells.	Head and neck squamous cell carcinoma; non-small cell lung carcinoma	(Frederick et al., 2007; Rho et al., 2009)
Gemcitabine	Gemcitabine-resistant cells have EMT features; EMT cells have high expression of Notch; EMT contributes to drug resistance	Pancreatic cancer cells	(Arumugam et al., 2009; Shah et al., 2007; Wang et al., 2009c)
Lapatinib	Lapatinib-resistant cell lines exhibited EMT features.	Breast cancer	(Konecny et al., 2008)
Oxaliplatin	Chronic oxaliplatin resistance induced EMT	Colorectal cancer cells	(Yang et al., 2006)
Paclitaxel	Paclitaxel-resistant cells showed EMT characteristics.	Ovarian carcinoma cells	(Kajiyama et al., 2007)
Tamoxifen	Tamoxifen resistance promotes EMT-like behavior and involved regulation of beta-catenin phosphorylation and Pin1 expression	Breast cancer cells	(Hiscox et al., 2006; Kim et al., 2009)
Doxorubicin	Doxorubicin activates TGFβ signaling and EMT	Human and murine breast cancer cells	(Bandyopadhyay et al., 2010)