Table 1.
High-Performance Liquid Chromatography: Conditions for Profiling Serum and Urine Samplesa
| Column | Luna phenyl-hexyl 3-μm packing, 150 × 3.0 mm ID | ||
| Guard cartridge | Phenyl, 3 μm, 4 × 2 mm ID | ||
| Mobile phases | A 1000:1 (v/v) water:TFA B 900:100:1 (v/v) MeOH:THF:TFA | ||
| Mobile phase gradient | Time (min) | %A | %B |
| 0 | 95 | 5 | |
| 35 | 65 | 35 | |
| 37 | 5 | 95 | |
| 40 | 5 | 95 | |
| 41 | 95 | 5 | |
| Flow rate | 0.300 ml/min | ||
ID, inside diameter; TFA, trifluoroacetic acid; MeOH, methanol; THF, tetrahydrofuran.