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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Cell Signal. 2010 Aug 21;23(1):99–104. doi: 10.1016/j.cellsig.2010.08.008

Fig. 3.

Fig. 3

Effect of wild-type ELMO1 and mutant ELMO1 on COX-2-mediated fibronectin gene expression. (A) Luciferase assay with the fibronectin promoter in THMC co-introduced with AdCOX-2WT, ELMO1WT or ET625. * P < 0.001, ** P < 0.05, *** P < 0.05 by two-tailed Student t-test. (B) THMC transfected with the indicated plasmids were infected with AdCOX-2WT, and lysates were immunoprecipitated with anti-Flag antibody. Precipitated COX-2 and DOCK 180 were determined by immunoblotting. Expression of the endogenous proteins or overexpressed proteins was determined by immunoblotting of TCL. Data are representative of three independent experiments. All data in A are means ± s.e.m from at least three separate experiments, each performed in duplicate.