Table 1.

Loci associated with diabetic nephropathy in a GWAS of the GoKind collection and their association with diabetic nephropathy in other studies.

					GoKind GWAS (Pezzolesi et al.)†		DCCT/EDIC (Pezzolesi et al.)‡		JAPAN (Maeda et al.)∥
Representative SNP	Chr	Mb	Nearest gene	Risk allele	OR	p value	HR	p value	OR	p value
rs39075	7p	29.2	CPVL/CHN2	G	1.43	6.5 × 10−7	0.85	NS	1.07	0.19
rs1888747	9q	85.3	FRMD3	G	1.45	6.3 × 10−7	1.33§	0.02	0.96	0.51
rs451041	11p	3.0	CARS	A	1.36	3.1 × 10−6	1.32	0.01	1.06	0.30
rs1411766	13q	109.1	IRS2/MYO16	A	1.41	1.8 × 10−6	1.17	0.11	1.26	0.004

^†820 cases/885 controls with T1D,

^‡132 events/1304 subjects with T1D,

^∥1535 cases/1915 controls with T2D from four different studies.

^§Data refer to rs1888746, which is in complete LD (r2=1.00) with rs1888747.