Table 1.
Summary of demographic data and immunohistologic findings in autopsy specimens
| Case | Age (yr)-Sex | Postmortem delay (hr) | Brain weight (g) | Cerebral cortex | Aβ40 artery / arteriole | Aβ42 artery / arteriole | Aβ40 capillary | Aβ42 capillary |
|---|---|---|---|---|---|---|---|---|
| SA1 | 86-F | 19 | 970 | RO | + | + | + | − |
| SA2 | 85-M | 4 | 1250 | RO | − | − | − | − |
| SA3 | 87-F | 14 | 925 | LO | + | + | + (PD) | − |
| SA4 | 83-F | 24 | 1320 | RO | + | + | + (PD) | + (PD) |
| SA5 | 88-M | 14 | 1120 | RF | + | + | + (PD) | + (PD) |
| SA6 | 79-M | 21 | 1100 | LO | + | + | + | + (PD) |
| SA7 | 96-F | 12 | 920 | RO | + | + | − | + (PD) |
| MA1 | 88-F | 6 | No record | LO | − | − | − | − |
| MA2 | 74-M | 12 | 1160 | RO | − | − | − | − |
| MA3 | 90-M | 13 | 1110 | RO | − | − | − | − |
| MA4 | 65-F | 9 | 1160 | RF | − | − | − | − |
| MA5 | 72-F | 16 | 950 | RO | − | − | − | − |
| MA6 | 91-F | 4 | 1120 | RO | + | + | − | − |
| MA7 | 63-F | 18 | 950 | LO | − | − | − | − |
| MA8 | 69-F | 16 | 910 | RO | − | + | − | + |
| MA9 | 89-M | 15 | 1165 | RO | − | − | − | − |
| OC1 | 72-F | 16 | 1150 | RO | − | − | − | − |
| OC2 | 86-M | 28 | 1170 | RO | − | − | − | − |
| OC3 | 67-M | 22 | 1670 | LO | − | − | − | − |
| OC4 | 81-M | 24 | 1470 | RO | − | − | − | − |
| OC5 | 71-M | 26 | 1270 | RO | − | − | − | − |
| YC1 | 43-F | 30 | No record | RO | − | − | − | − |
| YC2 | 35-F | 15 | 1560 | LO | − | − | − | − |
| YC3 | 23-M | 21 | 1570 | LO | − | − | − | − |
| YC4 | 13-M | 22 | 1430 | LO | − | − | − | − |
Abbreviations:Aβ, β-amyloid; SA1-SA7, brains of Alzheimer's disease patients with severe cerebral Aβ angiopathy (Vonsattel grade III); MA1-MA9, brains of Alzheimer's disease patients with mild cerebral Aβ angiopathy (Vonsattel grade I); OC1-OC5, brains of non-demented old controls; YC1-YC4, brains of non-demented young controls; F, female; M, male; RO, right occipital; LO, left occipital; RF, right frontal; “+”, presence; “−”, absence; PD, pericapillary deposits (ie, Aβ deposits radiating from Aβ-laden capillaries into the surrounding neuropil).