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. Author manuscript; available in PMC: 2011 Nov 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2010 Sep 9;249(1):1–7. doi: 10.1016/j.taap.2010.08.024

Figure 4.

Figure 4

Effect of exogenous AMH on VCD-induced follicle loss. PND4 F344 rat ovaries were cultured in culture medium or medium containing VCD (30 μM) with or without recombinant human AMH (100, 200, 400 ng/ml; labeled AMH 100, AMH 200 or AMH 400, respectively) for 8 days. Ovaries were collected and processed for histological evaluation as described in Materials and Methods. Healthy follicles in every 12th section were counted. Values indicate the mean number of healthy (A) primordial follicles, (B) small primary follicles, (C) large primary follicles, (D) secondary follicles counted per ovary ± SEM; n = 5 ovaries per treatment group (A-D); *P < 0.05 different from control.