Table 1.
Properties of AMPA and NMDA EPSCs in FS interneurons in the rat prefrontal cortex
| CI (RI > 0.7) n= 19 (21.8%) | CP (RI < 0.7) n= 68 (78.2%) | P value | |
|---|---|---|---|
| Age (days) | 43.9 ± 7.29 | 46.4 ± 3.77 | 0.754 |
| (PD15–101) | (PD15–108) | ||
| Rectification index | 1.23 ± 0.06 | 0.21 ± 0.02 | <0.0001 |
| (0.76–1.78) | (0.01–0.64) | ||
| Resting membrane potential (mV) | −66.6 ± 3.33 | −67.1 ± 1.22 | 0.733 |
| Input resistance (MΩ) | 210.3 ± 30.7 | 191.0 ± 11.6 | 0.240 |
| AP threshold (mV) | −35.7 ± 2.21 | −33.7 ± 1.34 | 0.356 |
| AP half-width (ms) | 0.56 ± 0.02 | 0.55 ± 0.03 | 0.868 |
| Afterhyperpolarization (mV) | 16.2 ± 3.46 | 14.4 ± 1.76 | 0.655 |
| AMPA EPSC amplitude (pA) | 72.4 ± 14.2 | 78.6 ± 7.2 | 0.616 |
| AMPA EPSC decay (ms) | 4.25 ± 0.53 | 3.92 ± 0.42 | 0.925 |
| AMPA EPSC charge (pC) | 0.65 ± 0.15 | 0.87 ± 0.10 | 0.421 |
| AMPA EPSC 20–80% rise time (ms) | 0.65 ± 0.06 | 0.67 ± 0.05 | 0.966 |
| NMDA EPSC amplitude (pA) | 53.4 ± 12.05 | 8.87 ± 1.58 | <0.0001 |
| NMDA/AMPA ratio | 1.02 ± 0.12 | 0.19 ± 0.02 | <0.0001 |