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. 2010 Jun 29;18(9):1683–1688. doi: 10.1038/mt.2010.134

Figure 2.

Figure 2

Immunoreactivity of the rescued dystrophin in CA1 hippocampus. (a) Dystrophin-IR in stratum pyramidale (SP) and proximal stratum radiatum (SR) of CA1 hippocampus in WT and mdx mice injected with PBS and in AAV-treated mdx mice. Each panel represents projection of five-image stacks. Arrows: pyramidal-cell bodies in SP. Bar = 20 µm. (b) Area covered by dystrophin-IR in SP as % of WT. (c) Area covered by dystrophin-IR in SR as % of WT. (d) Fraction area covered by dystrophin-IR in the SR (% of total SP + SR). *P < 0.05; **P < 0.001. AAV, adeno-associated virus; IR, immunoreactivity; PBS, phosphate-buffered saline; WT, wild type.