Skip to main content
. 2010 Jun 22;18(9):1606–1614. doi: 10.1038/mt.2010.105

Figure 5.

Figure 5

Exosomal curcumin can protect mice from LPS-induced septic shock. (a) Curcumin or exosomal curcumin (4 mg/kg) was injected i.p. into C57BL/6j mice together with LPS (18.5 mg/kg, Sigma-Aldrich). An equal amount of EL-4 exosomes used in the exosomal curcumin was used in the control. Mouse mortality was monitored over a period of 4 days. Data represented 10 mice/group and pooled from two experiments (**P < 0.01, *P < 0.05). (b) Exosomal curcumin can decrease IL-6 and TNF-α secretion in LPS-stimulated mice. The sera were collected 16 hours after LPS injection, and IL-6 and TNF-α concentrations in the sera were determined using an enzyme-linked immunosorbent assay (**P < 0.01).