Table 1.
Medium | pH | Osmolality | Buffer | Comments |
---|---|---|---|---|
Human serum | 7.4 | 289 (280–310) | Bicarbonate | Bicarbonate is a suboptimal pH buffer for cold storage solutions |
Normal saline | 5.0 | 308 | None | Extracellular balance |
Lactated Ringer’s | 6.5 | 273 | Lactate | Extracellular balance |
Plasma-lyte A | 7.4 | 294 | Acetate gluconate | Extracellular balance |
HypoThermosol-FRS | 7.6 | 360 | HEPES | Intracellular-like balance |
HTK-Custodial | 7.4–40C 7.25–RT | 310 | Histidine | Intracellular-like balance Tryptophan (membrane stabilizer) Ketoglutarate (energy substrate) |
Sterile water | 5.5 | 0 | None | Mistakenly using this as a storage solution can kill all grafts |