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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Expert Rev Hematol. 2010 Aug 1;3(4):469–483. doi: 10.1586/ehm.10.33

Figure 2. Adoptive transfer of CD4+Foxp3+ T cells from Factor VIII plasmid-treated HemA/Foxp3-Tg mice can modulate anti-FVIII immune responses in recipient hemophilia A mice.

Figure 2

CD4+ T cells were isolated from the spleens of HemA/Foxp3-Tg mice 2 weeks post-FVIII plasmid treatment and adoptively transferred into naive HemA mice. Recipient mice, as well as a control group of naive hemophilia A mice, were subsequently challenged with FVIII plasmid injection 1 day following adoptive transfer.