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. 2010 Nov;16(11):2120–2130. doi: 10.1261/rna.2227710

FIGURE 4.

FIGURE 4.

Homozygous dMRPEY08633 mutants die during the second larval instar. (A) A bimodal pattern of mortality was observed, with ∼70% of individuals dying 5–6 d AED. The remaining individuals lingered as second instar larvae for up to 17 d compared with control populations, which reached adulthood at ∼10 d AED. (B) Representative mouth hook from a homozygous dMRPEY08633 larva examined post mortem. All mouth hooks had two to four teeth, indicative of the second instar stage. (Below) Approximate development timeline for wild-type individuals. (dMRP) dMRPEY08633.