Table 1.
Clinical characteristics of the 11 subjects with recurrent ACALD
| A. General Characteristics | ||
|---|---|---|
| Characteristic | No. | |
| Gender | All women | |
| Age | 49±3 years | |
| Time posttransplant when histology positive for ACALD | 18±4 months | |
| B. Autoantibody status | ||
| Autoantibodies positive | Pre-OLTx | Post-OLTx |
| ANA | 6/11 | 5/11 |
| Antimicrosomal | 11/11 | 11/11 |
| Antithyroglobulin | 10/11 | 9/11 |
| Antismooth muscle | 8/11 | 8/11 |
| Symptomatica | 11/11 | 11/11 |
| Fivefold elevation of transaminases | 5/11 | 8/11 |
| Twofold increase in gamma-globulin levels | 11/11 | 11/11 |
a
Symptoms including arthritis, fatigue, and abdominal (hepatic) discomfort.